甘露醇作为脱水剂治疗脑水肿已广泛应用 ,然而大量甘露醇应用对肾功能可能产生不良影响。近年来 ,有文献报道 ,小剂量甘露醇与常规剂量有相似的脱水效果。我们采用随机、单盲、交叉给药方法 ,观察比较了 6名健康青年医务人员在给予不同剂量甘露醇后不同时间的分次尿量和总尿量 Mannitol has been widely used as a dehydrating agent in the treatment of cerebral edema, however, extensive mannitol administration may have adverse effects on renal function. In recent years, it has been reported in the literature that small doses of mannitol have similar dehydration effects as conventional doses. We used a randomized, single-blind, cross-feeding method, observed and compared six healthy young medical staff in different doses of mannitol at different times after the fractionated urine volume and total urine output