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一切活的生物组织,无论是在休止状态,还是在进行功能活动时,都显示有电的现象。应用微电极研究心室肌纤维的电活动,如图1示。将两个引导电极置于静止状态的心肌纤维表面,由于其细胞膜呈极化状态,即膜外为正,膜内为负,电极间无电位差产生(图1A～B)。若将其中的一个微电极,刺入心肌纤维内,则立即描记出跨膜电位,如图1B～C,表明细胞内的电位比细胞外大约低90mv。这种静止细胞的负跨膜电位,就叫做休止电位。当心肌纤维兴奋时,原来的极化状态被破坏,细胞膜的内
All living biological organizations, whether in the state of rest, or in functional activities, have shown the phenomenon of electricity. The application of microelectrodes to study the electrical activity of ventricular muscle fibers, shown in Figure 1. The two guiding electrodes were placed on the surface of quiescent myocardial fibers. Because of the polarized state of the cell membrane, that is, the membrane was positive and the membrane was negative, there was no potential difference between the electrodes (FIGS. 1A-B). If one of the microelectrodes pierces the myocardial fibers, the transmembrane potential is immediately traced as shown in FIGS. 1B-C, indicating that the intracellular potential is about 90 mv lower than the extracellular level. The negative transmembrane potential of this quiescent cell is called the resting potential. When the muscle fibers are excited, the original polarization state is destroyed, the membrane inside