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目的探究马来酸依那普利叶酸片对H型高血压患者血清Hcy及血压水平的影响。方法选择2016年1月—2017年1月收治的H型高血压患者160例,根据随机数表法将所有患者分为两组,每组80例。对照组采用常规马来酸依那普利片治疗,观察组予以马来酸依那普利叶酸片治疗,观察比较两组血压和血清Hcy水平变化及不良反应发生情况。计量资料比较采用t检验,P<0.05为差异有统计学意义。结果治疗前,两组血清Hcy及血压水平相比,差异无统计学意义(均P>0.05);治疗后,两组血清Hcy及血压水平均降低,且观察组低于对照组,差异有统计学意义(均P<0.05);两组患者治疗期间均未见明显不良反应。结论马来酸依那普利叶酸片能有效改善H型高血压患者血清Hcy及血压水平。
Objective To investigate the effect of enalapril maleate folic acid tablets on serum Hcy and blood pressure in patients with Hypertension. Methods From January 2016 to January 2017, 160 patients with H-type hypertension were enrolled. All patients were divided into two groups according to the random number table (n = 80). The control group was treated with conventional enalapril maleate tablets. The observation group was treated with enalapril maleate folic acid tablets. Changes of blood pressure and serum Hcy levels and the incidence of adverse reactions were observed in the two groups. Measurement data were compared using t test, P <0.05 for the difference was statistically significant. Results Before treatment, there was no significant difference in serum Hcy and blood pressure between the two groups (all P> 0.05). After treatment, serum Hcy and blood pressure decreased, and the difference between the two groups was statistically significant Significance (both P <0.05). No adverse reactions were observed in both groups during treatment. Conclusion Enalapril maleate folic acid tablets can effectively improve serum Hcy and blood pressure in patients with Hypertension.