镉的环境污染问题已经引起广泛重视,在进行镉污染对人体健康影响的调查时,尚缺乏灵敏特异诊断指标。在日本痛痛病地区和镉污染地区居民的调查已经用低分子尿蛋白作为早期诊断肾小管损害的指标。尿蛋白的分析方法很多,过去曾用①柱凝胶过滤法,②薄层凝胶过滤法,③SDS园盘电泳法,④醋酸纤维电泳法,近来在免疫学定量方面发展很快,自⑤交 Cadmium pollution of the environment has attracted widespread attention, in the investigation of the impact of cadmium pollution on human health, there is a lack of sensitive and specific diagnostic indicators. Surveys in Japan’s pain-prone areas and cadmium-contaminated areas have used low-molecular-weight urine protein as an early indicator of renal tubular damage. There are many urinary protein analysis methods used in the past ① column gel filtration, ② thin gel filtration, ③ SDS plate electrophoresis, ④ cellulose acetate electrophoresis, the rapid development of quantitative immunology recently, since ⑤ pay