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目的在多固定野三维适形放射治疗中,为科学、准确、有效地使用铅挡块与多叶准直器提供重要依据;以便较好地处理好肿瘤组织和周围正常组织间的剂量关系,使肿瘤得到最大限度的局部控制而周围正常组织和器官的放射性损伤最小,提高疗效。方法分析比较多固定野三维适形放射治疗中铅挡块与MLC的适形度、漏射剂量率、不规则靶区边缘1cm处剂量率、物理半影、质量保证和质量控制、CT扫描方向肿瘤计划靶区大小不是MLC叶片整数倍、每次治疗时间等。结果在多固定野三维适形放射治疗中,铅挡块与多叶准直器各有优缺点。结论该研究成果可用于指导多固定野三维适形放射治疗中,铅挡块与多叶准直器的选择使用。
Objective To provide an important basis for the scientific, accurate and effective use of lead block and multi-leaf collimator in multiple fixed-field three-dimensional conformal radiotherapy in order to better handle the dose relationship between the tumor tissue and the surrounding normal tissue, So that the maximum local control of the tumor and surrounding normal tissues and organs to minimize radiation damage and improve efficacy. Methods The conformality, leakage dose rate, dose rate at 1cm at the edge of irregular target, physical penumbra, quality assurance and quality control, CT scanning direction The tumor target area size is not an integer multiple of MLC leaves, each treatment time and so on. Results In multiple fixed field three-dimensional conformal radiotherapy, lead stopper and multi-leaf collimator each have advantages and disadvantages. Conclusion The results of this study can be used to guide the choice of lead block and multi-leaf collimator in multi-fixed-field 3D conformal radiotherapy.