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目的：探讨肌电图(EMG)、肌活检对神经肌肉病的诊断价值,比较肌电图、肌活检及初始临床诊断3者之间的关系。方法：将139例神经肌肉病分成肌病和运动神经元病2组进行研究。结果：肌病组(121例)85．1% (103/121)肌活检和72．7%(88/121)肌电图呈肌源性损害；运动神经元病组(18例)83%(15/18)肌活检和100%(18/ 18)肌电图呈神经源性损害。结论：肌活检对肌病明确诊断可提供直接信息,对运动神经元病只能做出神经源性损害结果,缺乏特异性。肌电图对神经肌肉病只能做出分类诊断；单纯凭借初始临床资料易导致该类疾病误诊。
Objective: To investigate the diagnostic value of electromyography (EMG) and muscle biopsy in neuromuscular disease, and to compare the relationship among EMG, muscle biopsy and initial clinical diagnosis. Methods: 139 cases of neuromuscular diseases were divided into two groups: myopathy and motor neuron disease. Results: 85.1% (103/121) muscle biopsies and 72.7% (88/121) EMGs were myogenic lesions in myopathy group (121 cases); motor neuron disease group (18 cases) 83% (15/18) muscle biopsies and 100% (18 of 18) EMG neurogenic lesions. CONCLUSIONS: Muscular biopsies provide direct information on the definitive diagnosis of myopathy and lack of specificity for only neurogenic lesions in motor neuron disease. EMG can only make a classification of neuromuscular disease diagnosis; simply by virtue of the initial clinical data easily lead to misdiagnosis of such diseases.