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观察了50例糖尿病患者血循环功能及心脏分泌激素心钠素(ANP)均有不同程度的改变。其中左室喷血阻抗、心搏指数改变明显。ANP 明显减低,且与血压、左室喷血阻抗、心肌耗氧指数呈正相关,而与血管扩张系数、心搏指数呈负相关。认为糖尿病血循环功能异常系血管病变的早期指标。ANP发生相应变化的原因主要系心脏内分泌功能衰减及血管神经病变,致内分泌内在调节机制紊乱所致。
Fifty patients with diabetes mellitus were observed to have varying degrees of circulatory function and cardiac secretion of atrial natriuretic peptide (ANP). Which left ventricular ejection impedance, cardiac index changed significantly. ANP was significantly reduced, and with blood pressure, left ventricular ejection resistance, myocardial oxygen consumption index was positively correlated with the vasodilator index, cardiac index was negatively correlated. Diabetes blood circulation abnormalities that vascular disease early indicators. The reason for the corresponding changes in ANP is mainly due to the attenuation of cardiac endocrine function and vascular neuropathy, resulting in the disorder of endocrine intrinsic regulation mechanism.