论文部分内容阅读
观察了BALB/c小鼠胚胎至成年脾发育分化的组织学和组织化学变化.(1)胚胎12天,胃背系膜内出现由间充质细胞形成的脾原基.此后,脾窦、网状细胞及淋巴细胞相继出现;生后1天出现动脉周围淋巴鞘;以后逐渐形成脾小结.(2)胚胎13天时脾中出现糖原和RNA颗粒,并渐增多,生后1周糖原量骤减,2周至成年为阴性.RNA则在白髓中少,红髓中多.(3)碱性磷酸酶在17天胚胎脾内出现阳性细胞,以后增多.(4)酸性磷酸酶在胚胎17天脾内出现,以巨噬细胞和网状细胞中活性强.(5)胚胎15天时出现非特异性酯酶阳性的淋巴细胞;胚胎16天出现乙酸胆碱脂酶阳性的巨核细胞,至成年增多增大.
The histological and histochemical changes of BALB / c mouse embryos to adult spleen development and differentiation were observed. (1) Splenic primordium formed by mesenchymal cells appeared in the gastric dorsal mesangial membrane Reticulocytes and lymphocytes appeared one day after birth, peripheral arterial lymphoid sheath appeared, and then gradually formed splenic nodules. (2) embryos on the 13th day in the spleen glycogen and RNA particles, and gradually increased more than 1 week after birth, glycogen (2) alkaline phosphatase in the 17-day-old embryo spleen positive cells, later increased. (4) acid phosphatase in the white matter of the less, red pulp more. The embryos appeared in the spleen on the 17th day, and were highly active in the macrophages and reticulocytes. (5) Non-specific esterase-positive lymphocytes appeared on the 15th day of embryo. Chymotrypsin- Adulthood increases.