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目的:分析高频电波刀联合阴道镜下多点活检治疗宫颈上皮内瘤变(CINⅡ～Ⅲ)的临床效果。方法:回顾性分析了2005年1月～2007年6月在武警吉林部队医院妇科门诊宫颈疾病治疗中心经阴道镜下多点活检病理诊断为CINⅡ～Ⅲ级,继之行高频电波刀术治疗的78例患者的临床资料。采用自身对照,对比分析阴道镜下多点活检和高频电波刀治疗后的病理检查结果及复发情况。结果:78例CINⅡ～Ⅲ患者,阴道镜下多点活检与高频电波刀术病理诊断符合率为70.51%(55/78),升级8.97%(7/78),降级20.51%(16/78),阴道镜下多点活检与高频电波刀术病理诊断差异有统计学意义(P<0.05)。高频电波刀治愈率为93.42%(71/76),复发率为2.63%(2/76)。结论:高频电波刀是治疗CINⅡ～Ⅲ级安全有效的方法,其治愈率高,术后并发症少;在诊断CINⅡ～Ⅲ级和早期宫颈癌方面,阴道镜下宫颈多点活检联合高频电波刀术有更高的临床价值。
Objective: To analyze the clinical effect of high frequency electrosurgical knife combined with colposcopy multipoint biopsy in the treatment of cervical intraepithelial neoplasia (CINⅡ ~ Ⅲ). Methods: From January 2005 to June 2007, patients underwent gynecological clinic cervical disease treatment center of Jilin Provincial Armed Police Corps by multi-point colposcopy biopsy pathological diagnosis of CIN Ⅱ ~ Ⅲ, followed by high-frequency electric wave surgery Of 78 patients with clinical data. Using self-control, comparative analysis colposcopy multi-point biopsy and high-frequency radio wave knife after the pathological examination results and recurrence. Results: In 78 patients with CINⅡ ~ Ⅲ, colposcopy and multifocal biopsy showed the coincidence rate of 70.51% (55/78), 8.97% (7/78), 20.51% (16/78) ), Colposcopy and multi-point biopsy and pathological diagnosis of high-frequency radio-wave difference was statistically significant (P <0.05). The cure rate of high frequency electric wave knife was 93.42% (71/76), the recurrence rate was 2.63% (2/76). Conclusion: The high frequency electric wave knife is a safe and effective method for the treatment of CINⅡ ~ Ⅲ, which has high cure rate and few postoperative complications. In the diagnosis of CINⅡ ~ Ⅲlevel and early cervical cancer, colposcopy biopsy combined with high frequency Radiofrequency surgery has a higher clinical value.