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目的 观察男性甲亢性低钾周瘫（THPP）患者血清甲状腺激素、黄体生成素（LH）、卵泡刺激素（FSH）、催乳素（PRL）、孕酮（P）、总睾酮（T）、雌二醇（E2）的水平变化。方法分析了38例男性甲亢患者血清钾、总三碘甲腺原氨酸（TT3）、游离三碘甲腺原氨酸（FT3）、总甲状腺素（TT4）、游离甲状腺素（FT4）、促性腺激素与性激素的水平，其中THPP患者19例，无THPP的甲亢患者19例。结果（1）甲亢患者中THPP组血清TT3、FT3、TT4及T水平明显高于无THPP组（P均＜0．01）。血清LH、FSH、PRL、P及E2水平两组无显著差异性。（2）血清TT3、TT4、FT3及T与血清钾水平呈负相关关系，血清TT3与T水平呈正相关关系。结论男性甲亢患者血清甲状腺激素水平明显升高者易发生THPP；伴有THPP的男性甲亢患者T水平升高，其原因尚有待进一步研究。
Objective To observe the changes of serum thyroid hormone, luteinizing hormone (LH), follicle stimulating hormone (FSH), prolactin (PRL), progesterone (P), total testosterone Changes in diol (E2) levels. Methods Serum potassium, total triiodothyronine (TT3), free triiodothyronine (FT3), total thyroxine (TT4) and free thyroxine (FT4) in 38 patients with hyperthyroidism were analyzed. Gonadal hormones and sex hormones, including 19 cases of THPP patients, 19 cases of hyperthyroidism without THPP. Results (1) The levels of TT3, FT3, TT4 and T in THPP group were significantly higher than those in THPP group (all P <0.01). Serum LH, FSH, PRL, P and E2 levels were no significant difference between the two groups. (2) There was a negative correlation between serum TT3, TT4, FT3 and T and serum potassium level, and serum TT3 was positively correlated with T level. Conclusions The level of serum thyroid hormone in patients with hyperthyroidism was significantly higher than those prone to THPP; THPP associated with THPP increased in patients with hyperthyroidism, the reason remains to be further studied.