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视网膜脱离膜形成实质上是玻璃体视网膜增殖粘连(VRPA)。我们从玻璃体手术中取得的整片的膜共85例,进行了光镜、电镜研究。有四种主要细胞:纤维样星状胶质细胞、吞噬细胞、纤维细胞和过渡型细胞。过渡型细胞可能是星状胶质细胞或 RPE 细胞向纤维细胞转化过渡的中间型细胞。基质中胶原原纤维直径100-150(?),有时胞浆内微丝与胞浆外胶原原纤维打成一片,这种纤维样星状细胞很可能是产生胶原原纤维形成 VRPA 的主要细胞,也是引起 VRPA 收缩的主要细胞。VRPA 存在于视网膜脱离整个过程,甚至在破口形成以前,此时视网膜色素上皮细胞还不可能进入玻璃体。
Retinal detachment membrane formation is essentially vitreoretinal proliferation adhesion (VRPA). We obtained from the vitreous surgery the whole film a total of 85 cases were light and electron microscopy. There are four main types of cells: fibrillar astrocytes, phagocytes, fibroblasts and transitional cells. Transitional cells may be intermediate cells that transition from astrocytes or RPE cells to fibroblasts. Collagen fibrils in the matrix diameter of 100-150 (?), Sometimes intracytoplasmic filaments and extracellular plasminogen fibrillation, the fibrous stellate cells is likely to be the main cells producing collagen fibrils to form VRPA, but also caused VRPA contraction of the main cells. VRPA exists in the entire process of retinal detachment, and even before the formation of a tear, retinal pigment epithelial cells at this time is still not possible to enter the vitreous.