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目的:探讨阻塞性睡眠呼吸暂停低通气综合征(OSAHS)与高血压的关系。方法:对52例高血压并发打鼾的患者进行睡眠呼吸监测仪检查及动态血压检查,分析患者呼吸紊乱指数(AHI)、夜间最低血氧饱和度(LSaO2)与血压升高程度及昼夜节律之间的关系。结果:以AHI分组,对各组间高血压程度进行比较,AHI与血压的高低呈正相关,夜间血压增高幅度明显高于白昼(P<0.01);且收缩压增高幅度高于舒张压(P<0.001),差异具有统计学意义。AHI值越大,血压波动亦越大。LSaO2比AHI更敏感,与高血压程度为负相关。结论:OSAHS作为高血压的危险因素,其AHI、夜间低氧血症程度均与高血压患者夜间血压升高程度相关。
Objective: To investigate the relationship between obstructive sleep apnea-hypopnea syndrome (OSAHS) and hypertension. Methods: Fifty-two patients with hypertension complicated with snoring were inspected by sleep-breathing monitor and ambulatory blood pressure test. The relationship between respiratory disturbance index (AHI), nighttime lowest oxygen saturation (LSaO2), blood pressure and circadian rhythm Relationship. Results: AHI was used to compare the degree of hypertension between groups. There was a positive correlation between AHI and blood pressure, nighttime blood pressure increased significantly (P <0.01), systolic blood pressure increased more than diastolic blood pressure (P < 0.001), the difference was statistically significant. The greater the AHI value, the greater the fluctuation of blood pressure. LSaO2 is more sensitive than AHI and negatively correlated with the degree of hypertension. Conclusion: OSAHS as a risk factor for hypertension, its AHI, nocturnal hypoxemia and hypertension are related to the degree of nocturnal increase in blood pressure.