为探讨预防肝硬化食管静脉曲张破裂出血简便、有效的方法,通过38例心得安与硝酸甘油合用与30例胃镜下五环套扎术两组比较,观察1年内再出血率。结果显示,服药组与五环套扎组比较再出血率服药组略低于五环套扎组(服药组10.53％,套扎组20.00％),无显著差异(P>0.05)。提示心得安与硝酸甘油合用疗效可靠、方法简便、价格低廉,宜作为预防肝硬化食管静脉曲张破裂出血的首选方法之一。 In order to explore a simple and effective method for prevention of esophageal variceal bleeding due to liver cirrhosis, 38 cases of propranolol and nitroglycerin were compared with 30 cases of endoscopic gastroscopic ligation. The rate of rebleeding within 1 year was also observed. The results showed that the rate of rebleeding in the medication group and the pentacycle ligation group was slightly lower than that in the pentacyclic ligation group (10.53% in the medication group and 20.00% in the ligation group), no significant difference (P> 0.05). Prompt Ann and nitroglycerin combined with reliable curative effect, simple method, low price, should be used as a prevention of cirrhosis of the esophageal variceal bleeding is one of the preferred method.