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目的了解博乐市抗结核组药对化疗工作的影响以及不良反应发生情况。方法由结防科医师提供病程记录、实验室及辅助检查结果。分析抗结核组药治疗效果及不良反应发生情况。结果 183例结核病患者,初治失败1例,发生不良反应29例(15.8%),严重不良反应主要为肝功能异常,其次是胃肠道反应和药物过敏反应。结论博乐市采用一线抗结核药品标准化疗方案中,不良反应发生率相对较低,但在一定程度影响了化疗工作的顺利进行。一过性肝功能异常是影响肺结核化疗的主要原因,应予重视。
Objective To understand the impact of anti-TB drugs on the work of chemotherapy in Bole and the incidence of adverse reactions. Methods The results were provided by the endodontist with course records, laboratory and laboratory tests. Analysis of anti-TB drug treatment and adverse reactions occurred. Results Among the 183 patients with tuberculosis, 1 had initial failure and 29 had adverse reactions (15.8%). The serious adverse reactions were mainly liver dysfunction, followed by gastrointestinal reactions and drug allergy. Conclusion Bole City, the use of first-line standard anti-TB drugs in the standard chemotherapy, the incidence of adverse reactions is relatively low, but to a certain extent, affected the smooth progress of chemotherapy. A transient liver dysfunction is the main reason that affects chemotherapy of tuberculosis, should pay attention to.