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采用病例对照研究的方法,随机前瞻性观察了生长抑素对48例急性胰腺炎的治疗作用。结果表明对轻型急性胰腺炎的病程、并发症的发生、预后均无显著性改变(P>0.05)。对伴有其它脏器衰竭的Ⅱ型重症胰腺炎的病程、病死率均无显著性作用(P>0.05),而对Ⅰ型重症胰腺炎腹痛的缓解、疗程的缩短、并发症的减少均有明显的疗效(P>0.05)。结果表明生长抑素在急性胰腺炎有重症倾向或重症早期应用可产生明显的疗效。
A case-control study was used to prospectively observe the therapeutic effect of somatostatin on 48 patients with acute pancreatitis. The results showed that no significant changes were found in the course of disease, complications and prognosis of patients with acute pancreatitis (P> 0.05). No significant effect was found on the course of disease and mortality of severe acute pancreatitis Ⅱ associated with other organ failure (P> 0.05), but the remission, duration of treatment and reduction of complications of type Ⅰ severe pancreatitis Have significant effect (P> 0.05). The results show that somatostatin in severe acute pancreatitis or severe early application can produce significant effect.