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目的:观察地衣芽孢杆菌活菌胶囊联合匹维溴铵治疗腹泻型肠易激综合征(IBS-D)的疗效,探讨肠道微生态制剂与离子通道阻滞剂治疗在腹泻型肠易激综合征中的应用。方法:将72例IBS-D患者随机分成两组,对照组37例,单用匹维溴铵治疗,治疗组35例,给予地衣芽孢杆菌活菌胶囊联合匹维溴铵治疗,治疗周期为4周,治疗结束后评价治疗效果。结果:治疗组总有效率为82.86%,对照组总有效率为56.76%,两组疗效差异有统计学意义(P<0.05)。结论:地衣芽孢杆菌活菌胶囊联合匹维溴铵治疗能有效改善IBS-D患者的临床症状,疗效显著,值得临床推广。
Objective: To observe the efficacy of Bacillus licheniformis combined with pinaverium bromide in the treatment of diarrhea-predominant irritable bowel syndrome (IBS-D), and to explore the effects of intestinal probiotics and ion channel blockers in the treatment of diarrhea-predominant irritable bowel syndrome Application of the sign. Methods: Seventy-two patients with IBS-D were randomly divided into two groups. The control group, 37 cases, treated with pinaverium bromide alone. The treatment group received 35 cases of Bacillus licheniformis combined with verapamil. The treatment period was 4 Week, evaluation of treatment after the end of treatment. Results: The total effective rate was 82.86% in the treatment group and 56.76% in the control group. The difference between the two groups was statistically significant (P <0.05). Conclusion: Bacillus licheniformis combined with pinaverium bromide can effectively improve the clinical symptoms of patients with IBS-D, the curative effect is significant, worthy of clinical promotion.