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1 临床资料全部病例均经形态学及组织化学确诊,年龄60～72岁,平均年龄65岁,男性16例,女性5例,其中,急非淋(ANLL)18例,组织细胞白血病、幼淋巴细胞白血病及毛细胞白血病各1例,其中,3例有骨髓增生异常综合征(MDS)病史.起病症状及病程,绝大多数患者以头晕、乏力及心悸等为首发症状14/21例)占 66.7%,其次为发热(5/21)占 24%,个别表现为出血、消瘦、腹胀及食欲减退等.这些表现往往导致患者就诊于其他科室,尤其是病初血象无明显异常患者,易延误诊断、3例由MDS转变来的急性白血病从确诊MDS到转变为急性白血病的时间为4～10个月,余18例患者出现症状至确诊急性白血病时间为2～8个月.
1 Clinical data All cases were confirmed by morphological and histochemical examinations, aged 60 to 72 years, mean age 65 years, male 16 cases, female 5 cases, among them, 18 cases of acute non-lymphocin (ANLL), histiocytic leukemia, lymph node There were 1 case of cell leukemia and 1 case of hairy cell leukemia, of which 3 cases had a history of myelodysplastic syndrome (MDS). Onset symptoms and course of disease, most patients had dizziness, fatigue, and palpitations as the first symptom 14/21 cases) Accounted for 66.7%, followed by fever (5/21) accounted for 24%, individual manifestations of bleeding, weight loss, abdominal distension and loss of appetite and so on. These performances often lead to patient visits in other departments, especially in patients with no obvious abnormal hemogram early, easy Delayed diagnosis, 3 cases of acute leukemia transformed from MDS from the diagnosis of MDS to acute leukemia for 4 to 10 months, the remaining 18 cases of symptoms to diagnosed acute leukemia for 2 to 8 months.