用反相高效液相色谱法测定对氨基酚及其杂质４，４′－二氨基二苯醚和苯胺的含量。选择了最佳色谱条件，提供了各组分的紫外光谱图。对氨基酚、苯胺和４，４′－二氨基二苯醚的线性范围分别为５～２５０，５～１５０和０．２～１２０ｍｇ／Ｌ，检测限分别为０．１，０．６和０．６ｎｇ。所建立的方法已应用于超声催化氢化法合成反应的跟踪监测和工业样品的分析鉴定，结果令人满意。 Determination of para-aminophenol and its impurities 4,4’-diaminodiphenyl ether and aniline using reversed-phase high performance liquid chromatography. The best chromatographic conditions were chosen and the UV spectra of each component were provided. The linear ranges of p-aminophenol, aniline and 4,4’-diaminodiphenyl ether were 5 ~ 250, 5 ~ 150 and 0.2 ~ 120 mg / L respectively with the detection limits of 0.1, 0.6 and 0 .6ng. The established method has been applied to the tracking and monitoring of synthesis reaction by ultrasonic catalytic hydrogenation and the identification of industrial samples with satisfactory results.