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肝细胞癌(HCC)是世界上10大恶性肿瘤之一,我国每年大约有十余万人死于HCC.目前手术仍是治疗HCC的重要手段,但术后复发转移率较高,即使小肝癌切除或行肝移植后其3年复发转移率仍超过50%.研究表明,HCC复发转移是患者体内滞留癌细胞的繁殖或微小转移灶生长的结果.因此,对HCC患者术前术后AFP进行检测,籍以提高肝癌术后复发或转移灶的检出率,可以指导临床及时调整治疗方案,改善复发转移患者的预后.1 材料方法1.1 病例材料 收集本院1992~1995年间经临床病理确诊的原发性肝癌24例中,男21例,女3例,年龄39~72岁,中位年龄56岁;无转移者12例,有转移者12例.另选肝转移癌MHC8例(肠癌4例、
Hepatocellular carcinoma (HCC) is one of the top 10 malignant tumors in the world. About 100,000 people die each year in HCC in China. The current operation is still an important means for the treatment of HCC, but the rate of recurrence and metastasis is higher after operation, even if the small hepatocellular carcinoma The rate of recurrence and metastasis at 3 years after resection or liver transplantation still exceeds 50%. Studies have shown that recurrence and metastasis of HCC is the result of proliferation of retained cancer cells in patients or the growth of small metastases. Therefore, preoperative and postoperative AFP is performed in HCC patients. Detection, in order to improve the detection rate of liver cancer after recurrence or metastasis, can guide the clinical timely adjustment of treatment programs to improve the prognosis of patients with recurrence and metastasis. 1 Materials and Methods 1.1 Case material collection of the hospital from 1992 to 1995 confirmed by clinical pathology In 24 cases of primary liver cancer, 21 were males and 3 were females, aged 39-72 years, median age 56 years; 12 cases without metastases, 12 cases with metastases, 8 cases with metastatic liver cancer (intestinal cancer) 4 cases