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利用人类免疫缺陷症病毒(HIV)包膜糖蛋白gp120亚单位作为疫苗预防HIV感染的策略遇到了困难,主要是野毒株的抵抗力问题。因此HIV疫苗的研制需要回到基本点重新考虑。
Using the human immunodeficiency virus (HIV) glycoprotein gp120 subunit as a vaccine strategy to prevent HIV infection has encountered difficulties, mainly due to the resistance of wild-type strains. Therefore, the development of HIV vaccine needs to be reconsidered back to the basic point.