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用除去维生素E的克山病病区粮配成的基础饲料,利用在该低硒低维生素E的基础饲料中补充α-生育酚和/或硒的饲料饲养大鼠,观察维生素E对硒代谢的影响。结果表明: (1)饲料硒水平相同时,维生素E可使肝组织中硒水平明显升高,对其它组织影响不大。 (2)不论硒缺乏时或是补充硒时,维生素E缺乏组动物的全血、心和肝谷胱甘肽过氧化物酶活力均低于补充维生素E组。心和肝中的差异较为明显。 (3)当相应两组大鼠的硒摄入量无明显差别时,不论是补硒组或是缺硒组,在饲料中补充维生素E均可使尿硒排出明显降低,硒在体内存留率增高。
With the removal of vitamin K Keshan disease ward allocated to the basic diet, the use of low-selenium in low vitamin E supplemented dietary basis of α-tocopherol and / or selenium feed rats observed vitamin E on selenium metabolism Impact. The results showed that: (1) When the dietary selenium levels were the same, vitamin E significantly increased the level of selenium in liver tissue, but had little effect on other tissues. (2) When selenium deficiency or selenium supplementation, vitality, heart and liver glutathione peroxidase activity of vitamin E deficient animals were lower than that of vitamin E supplementation group. The difference between heart and liver is more obvious. (3) When the corresponding two groups of rats selenium intake no significant difference, either selenium group or selenium deficiency group, vitamin E in the feed can make urinary selenium excretion decreased significantly, selenium in the body retention rate Increase.