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在外科感染中,耐药菌株,特别是革蓝氏阴性菌株的增多,使临床医生对氨基糖苷类抗生素越来越重视.虽然应用此类药品可能发生肾中毒和耳中毒的副作用,但由于它们抗菌谱广,对外科感染的主要细菌,包括革蓝氏阴性细菌有很高的敏感性,因此在临床上使用较广.目前常用的氨基糖苷类抗生素有艮他霉素、紫苏霉素、丁氨卡那霉素、乙基紫苏霉素和托普霉素.本文报道采用匈牙利“Biogal”公司出品的“Brulamycin”(托普霉素硫酸盐,每安瓿1
In surgical infections, the increase of drug-resistant strains, especially Gram-negative strains, has given clinicians more and more attention to aminoglycoside antibiotics.Although the side effects of nephrotoxicity and ototoxicity may occur due to the use of such drugs, Broad antibacterial spectrum, surgical infections of the major bacteria, including gram-negative bacteria have a high sensitivity, so widely used in clinical. Currently used aminoglycoside antibiotics are gentamycin, soramycin, Amikacin, ethyl musksomycin, and tobramycin.This paper reports the use of “Brulamycin” (tobramycin sulfate, manufactured by Hungarian “Biogal”