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目的了解哈尔滨市乙型病毒性肝炎(乙肝)病毒(HBV)流行和人群免疫情况,评价乙肝疫苗防治效果,为制定该市乙肝防治策略提供依据。方法采用多阶段随机抽样方法于2015年3月在哈尔滨市辖区内10个区、县(市)抽取1~59岁人群2 705人,开展流行病学调查,并采用酶联免疫(ELISA)法检测乙肝HBsAb、HBsAg、HBcAb。结果全市共检测2 705人,HBsAb总阳性率为59.33%,HBsAg总携带率为2.74%,HBcAb总阳性率为3.84%;1~岁组HBsAb阳性率高于其他各年龄组。结论大年龄组人群为乙肝防控重点对象,在成人中开展乙肝疫苗补种工作具有重要意义。
Objective To understand the epidemic situation of hepatitis B virus (HBV) and population immunity in Harbin and to evaluate the effect of hepatitis B vaccine in prevention and treatment of hepatitis B virus infection. Methods A total of 2 705 people from 1 to 59 years old were recruited from 10 districts and counties (districts) in Harbin area in March 2015 by epidemic investigation using enzyme-linked immunosorbent assay (ELISA) Detection of hepatitis B HBsAb, HBsAg, HBcAb. Results A total of 2 705 people were detected in the city. The total positive rate of HBsAb was 59.33%, the total carrier rate of HBsAg was 2.74%, and the positive rate of HBcAb was 3.84%. The positive rate of HBsAb in 1 ~ group was higher than that of other age groups. Conclusion The population of large age group is the key target of prevention and control of hepatitis B, and it is of great significance to carry out hepatitis B vaccine replanting in adults.