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本文报道71例慢性乙型肝炎患者的血清HBV-DNA、DNAP 及乙肝三系检测结果,同时进行临床观察和分析。结果表明血清HBV-DNA/DNAP 是检测HBV 特异的灵敏标记物,亦是HBV 复制和繁殖的指标,肝炎慢性化的标志。检测血清HBV-DNA/DNAP 不仅对诊断、临床分型及预后判断有较大实用价值,且在流行病学及肝炎防治工作中亦有重要意义。在某种程度上,还可弥补现行肝炎诊断标准和HBV 血清免疫学之不足,尤其在进一步识别CPH 和CAH 方面,将具有较大临床意义。
This paper reports 71 cases of patients with chronic hepatitis B serum HBV-DNA, DNAP and hepatitis B three-line test results, clinical observation and analysis. The results showed that serum HBV-DNA / DNAP is a sensitive marker for detection of HBV, a marker of HBV replication and reproduction, and a marker of chronic hepatitis. Detection of serum HBV DNA / DNAP is not only of great practical value in diagnosis, clinical classification and prognosis, but also of great significance in epidemiology and prevention and treatment of hepatitis. To some extent, but also make up for the current hepatitis diagnostic criteria and the lack of HBV serum immunology, especially in further identification of CPH and CAH, will be of great clinical significance.