论文部分内容阅读
目的探索辽宁省肾综合征出血热(HFRS)的流行规律,为制定防制策略提供科学依据。方法采用描述流行病学方法分析HFRS疫情,开展宿主动物监测,检测鼠密度和鼠带病毒率。结果 1962-2008年辽宁省累计报告HFRS病例53525例,年平均发病率为2.85/10万,死亡1042例,病死率为1.95%。家鼠型疫区不断扩大,混合型疫区逐年增加,病例地区分布由20世纪80年代的仅4个地区发展为现今病例覆盖全省14个市90%的县(区)。每年3-6月和11月至次年1月有2个流行高峰。年龄发病以15～60岁人群为主,职业以农民为主,约占70%。结论自21世纪初辽宁省HFRS疫情呈快速上升趋势,2005年以后由于在重点地区和人群中疫苗的大规模应用,疫情得到了有效遏制。
Objective To explore the prevalence of hemorrhagic fever with renal syndrome (HFRS) in Liaoning Province and to provide a scientific basis for making prevention and control strategies. Methods Descriptive epidemiological methods were used to analyze the epidemic situation of HFRS. Host animal monitoring was carried out to detect the rat density and the rate of murine virus. Results A total of 53,525 cases of HFRS were reported in Liaoning Province from 1962 to 2008, with an average annual incidence rate of 2.85 / 100 000, 1042 deaths and a case fatality rate of 1.95%. There has been an increase in the number of domestic mouse-type epidemic areas and the increase of mixed-type epidemic areas year by year. The distribution of cases has been expanded from only 4 areas in the 1980s to 90% of counties (districts) in 14 cities in the province today. From March to June each year and November to January next year, there are 2 popular peaks. The age of 15 to 60-year-old population-based, mainly to farmers, accounting for about 70%. Conclusion Since the early 21st century, the epidemic situation of HFRS in Liaoning Province has been rapidly increasing. Since 2005, the epidemic has been effectively checked due to the large-scale application of vaccines in key areas and populations.