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内支架植入胆管是Soehandra于1979年首次提出的一种内窥镜下胆管引流术.主要治疗恶性胆管狭窄,现已逐渐应用于良性胆管狭窄、术后胆管瘘、潴留性胆管结石、硬化性胆管炎、急性胆囊炎、胆管炎、胰腺炎等.十余年来,不同材料和形状的塑料支架、金属可扩张支架均已投入临床使用,主要是塑料支架.但问题是植入后期支架的阻塞.有报道,塑料支架3个月的阻塞率为20～30%,6个月达70%,这就大大限制了它的临床使用.为此,人们做了大量的基础和临床研究,试图阐明其原因和发生机理,以期寻求解决的办法.
Endoprosthesis of the biliary duct by Soehandra was first proposed in 1979 as an endoscopic biliary drainage for the treatment of malignant biliary strictures and has been gradually used in benign biliary strictures, postoperative bile duct fistulas, retention bile duct stones, sclerosing Cholangitis, acute cholecystitis, cholangitis, pancreatitis, etc. For more than ten years, plastic stents and metal expandable stents of different materials and shapes have been put into clinical use, mainly plastic stents, but the problem is that It has been reported that the 3-month block rate of plastic stents is 20-30%, which is 70% in 6 months, which greatly limits its clinical use.Therefore, a large number of basic and clinical studies have been attempted Clarify its causes and mechanism, with a view to finding solutions.