复方阿替卡因在患者口腔种植手术中的麻醉效果及对血压和心率的影响观察

来源 :药物流行病学杂志 | 被引量 : 0次 | 上传用户:wqvbqjxtid1
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目的:探讨复方阿替卡因用于口腔种植手术的麻醉效果,及对患者血压和心率的影响。方法:口腔种植手术患者60例随机分为观察组和对照组各30例。对照组予盐酸利多卡因麻醉,观察组予复方阿替卡因麻醉。比较两组麻醉效果、麻醉起效时间,两组患者麻醉即刻、术中及术后6 min血压、心率变化,以及药品不良反应发生情况。结果:观察组总有效率100.00%,显著高于对照组的80.00%(P<0.05);观察组麻醉起效时间明显低于低于对照组(P<0.05)。两组患者术后6 min时的收缩压、舒张压及心率均较麻醉即刻显著降低(P<0.05);且观察组患者术中、术后6 min的收缩压、舒张压及心率均显著低于对照组同期(P<0.05)。观察组药品不良反应发生率显著低于对照组(P<0.05)。结论:复方阿替卡因用于口腔种植手术中效果显著,具有重要临床研究价值。 Objective: To investigate the anesthetic effects of compound articaine used in oral implant surgery and its effect on blood pressure and heart rate. Methods: 60 cases of oral implant surgery were randomly divided into observation group and control group, 30 cases each. The control group was given lidocaine hydrochloride anesthesia, and the observation group was given compound articaine anesthesia. The effects of anesthesia, time to onset of anesthesia, immediate anesthesia, blood pressure and heart rate at 6 min after operation and postoperative 6 months were compared between the two groups and the occurrence of adverse drug reactions. Results: The total effective rate in the observation group was 100.00%, significantly higher than that in the control group (80.00%, P <0.05). The onset time of anesthesia in the observation group was significantly lower than that in the control group (P <0.05). The systolic blood pressure, diastolic blood pressure and heart rate of the two groups were significantly lower than those of the control group immediately after 6 min (P <0.05). The systolic blood pressure, diastolic blood pressure and heart rate of the two groups were significantly lower at 6 min after operation The same period in the control group (P <0.05). The incidence of adverse drug reactions in the observation group was significantly lower than that in the control group (P <0.05). Conclusion: The effect of compound articaine on oral implant surgery is significant and has important clinical value.
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