论文部分内容阅读
目的在考虑血管壁弹性条件下,分析颈内动脉血液流动和壁面切应力的分布特性,探讨动脉瘤破裂的生物力学因素。方法依据二维医学扫描图像构建三维个性化颈内动脉瘤模型。依据人体生理统计数据构建出血管壁模型。根据人体颈内动脉生理流动条件,利用有限体积法和有限元法模拟分析流固耦合作用下颈内动脉瘤中的血流动力学。结果在动脉瘤腔中有一个明显的涡旋存在,此涡旋流动的方向在心动周期内没有改变;在动脉瘤颈和动脉瘤壁面处存在一个壁面切应力值相对较大区域;在动脉瘤颈和动脉瘤顶有两个区域的Von Mises应力处于局部最大值。从材料强度角度考虑,这几个区域都是动脉瘤容易破裂的地方。结论通过流固耦合计算可以获得血管壁面应力分布特性,进而推断动脉瘤破裂的可能位置。
Objective To analyze the distribution characteristics of internal carotid artery blood flow and wall shear stress under the condition of vascular wall elasticity and to explore the biomechanical factors of aneurysm rupture. Methods A three-dimensional personalized internal carotid aneurysm model was constructed based on two-dimensional medical scanning images. Based on human physiological statistics to build a model of the vessel wall. According to the physiological flow condition of human internal carotid artery, the hemodynamics of the internal carotid aneurysm under fluid-structure interaction was simulated by finite volume method and finite element method. The results in the aneurysm cavity has a significant vortex exists, the direction of this vortex flow in the cardiac cycle did not change; in the aneurysm neck and aneurysm wall there is a relatively large wall shear stress in the region; in the aneurysm The Von Mises stress at the top of the neck and aneurysm is at a local maximum. From the perspective of material strength, these areas are where aneurysms easily rupture. Conclusion The stress distribution of the vascular wall can be obtained through the fluid-solid coupling calculation, and then the possible location of aneurysm rupture can be deduced.