本文研究鼓膜穿孔对畸变产物耳声发射(DPOAEs)的影响。用豚鼠做成不同大小和不同部位的鼓膜穿孔模型 ,有些模拟伴有外淋巴瘘或听骨链中断 ,以研究对 DPOAEs的影响。用 Grason- StadlerGS16 0系统测定最常用的 2 f1- f2 DPOAE。先记录鼓膜完整时的基准水平。然后在鼓膜前后或后 This article studies the effect of tympanic membrane perforation on distortion product otoacoustic emissions (DPOAEs). Models of perforation of the tympanic membrane of different sizes and locations were made with guinea pigs and some were modeled with periprosthetic or ossicular chain disruptions to study the effects on DPOAEs. The most commonly used 2 f1-f2 DPOAE was determined using the Grason-Stadler GS16 0 system. Record the baseline level of the tympanic membrane intact. Then before or after the tympanic membrane or after