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目的:评价头孢他啶和左氧氟沙星对心力衰竭伴肺部感染老年患者抗感染治疗的临床疗效。方法:选取医院2014年6月—2016年11月期间收治的心力衰竭伴肺部感染老年患者60例,将其随机分为观察组与对照组,每组30例;对照组患者给予常规方法治疗,观察组患者在对照组治疗基础上以降钙素原(Procalcitonin,简称PCT)测得值为依据,加用头孢他啶和左氧氟沙星抗感染治疗,比较两组患者治疗后的总有效率,以及治疗后患者咳嗽、咳痰、心力衰竭和肺部感染等症状的改善时间。结果:观察组患者临床治疗后的总有效率为93.33%高于对照组为70.00%(P<0.05);咳嗽、咳痰、心衰和肺部感染等症状治疗后改善时间分别为(5.1±2.0)d、(8.2±2.4)d和(8.5±2.9)d短于对照组为(8.3±2.5)d、(11.2±2.3)d和(11.4±2.8)d(P<0.05)。结论:以PCT值为依据采用头孢他啶和左氧氟沙星联用治疗老年心力衰竭伴肺部感染患者抗感染的临床疗效较为显著,可迅速改善肺部感染。
Objective: To evaluate the clinical efficacy of ceftazidime and levofloxacin in anti-infective treatment of elderly patients with heart failure and pulmonary infection. Methods: Sixty elderly patients with congestive heart failure and pulmonary infection were selected from June 2014 to November 2016 in the hospital. They were randomly divided into observation group and control group, with 30 cases in each group. Patients in the control group were given routine treatment The patients in the observation group were treated with ceftazidime and levofloxacin on the basis of the control group’s treatment with Procalcitonin (referred to as PCT), and the total effective rate after treatment was compared between the two groups, and the patients after treatment Cough, expectoration, heart failure and pulmonary infection and other symptoms of improvement time. Results: The total effective rate of the observation group after treatment was 93.33%, which was significantly higher than that of the control group (70.00%, P <0.05). The improvement time after the treatment of cough, sputum, heart failure and lung infection were 5.1 ± (8.2 ± 2.4) days and (8.5 ± 2.9) days were shorter than those in the control group (8.3 ± 2.5 days), (11.2 ± 2.3 days) and (11.4 ± 2.8 days) (P <0.05). Conclusion: The clinical efficacy of ceftazidime combined with levofloxacin in the treatment of elderly patients with heart failure and pulmonary infection based on the PCT value is significant, and the pulmonary infection can be rapidly improved.