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作者应用放射免疫法测定了50名正常人53例糖尿病患者血浆心钠素,肾素、血管紧张素Ⅱ水平。结果表明无并发症糖尿病病人和有慢性并发症糖尿病病人血浆心钠素均低于正常人。有慢性并发症糖尿病病人血浆心钠素低于无并发症者。糖尿病患者血浆心钠素浓度测定对预测糖尿病并发症及估计并发症预后有一定临床意义。
The authors used radioimmunoassay to determine plasma atrial natriuretic peptide, renin and angiotensin Ⅱ levels in 53 normal subjects. The results showed that plasma levels of atrial natriuretic peptide were lower in non-complication diabetic patients and patients with chronic complications of diabetes than in normal subjects. Patients with chronic complications of plasma atrial natriuretic peptide were lower than those without complications. The determination of plasma atrial natriuretic peptide in diabetic patients has some clinical significance in predicting the complication of diabetes and estimating the prognosis of complications.