Targeting lysophospholipid signaling as a therapeutic approach towards improved peripheral nerve reg

来源 :Neural Regeneration Research | 被引量 : 0次 | 上传用户:tkartist
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Peripheral nerve injury causes a partial or total loss of motor and sensory functions as a result of axonal disruption and subsequent axonal disintegration as well as denervation distal from the point of injury.Although peripheral nerves are,in contrast to the central nervous system,able to regenerate and reinnervate,functionality is not always restored completely due to insufficient reinnervation or remyelination,and injury may result in sequelae such as neuropathic pain.The Peripheral nerve injury causes a partial or total loss of motor and sensory functions as a result of axonal disruption and subsequent axonal disintegration as well as denervation distal from the point of injury. Although peripheral nerves are, in contrast to the central nervous system, able to regenerate and reinnervate, functionality is not always restored completely due to insufficient stromal reindeer or remyelination, and injury may result in sequelae such as neuropathic pain.The.
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