1963年尼雪俄考证实红细胞免疫粘附功能的物质基础是一种存在于多种细胞膜上的多态性单链跨膜糖蛋白,后来将其命名为Ⅰ型补体受体(complement receptor type1,CR1)。CR1分子是补体C3b、iC3b和C4b片段的受体,与C3b的亲和力最强。它在红细胞膜上含量最多,约占总量的95%。1979年Fe In 1963, Nitroso confirmed that the material basis of the erythrocyte immune adhesion function is a polymorphic single-stranded transmembrane glycoprotein that exists on various cell membranes and was later named as complement receptor type 1 CR1). The CR1 molecule is the receptor for the complement C3b, iC3b and C4b fragments and has the highest affinity for C3b. It is the most abundant in the erythrocyte membrane, accounting for about 95% of the total. 1979 Fe