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目的 观察肝动脉化疗栓塞 (TACE)结合B超引导下经皮肝穿瘤内注射 30 %醋酸 (PAI)治疗原发性巨块型肝癌的临床疗效。方法 对 2 3例中、晚期巨块型肝癌均先采用TACE ,术后 15～ 2 0d再在B超引导下PAI 2～ 3次。结果 治疗 2个周期后比较患者治疗前后AFP降低程度和肿块缩小情况 ,差异有显著性 (P <0 .0 1) ,1、2年生存率分别为 91%和 82 %。结论 TACE结合B超下PAI治疗中、晚期巨块型肝癌有较好的临床疗效。
Objective To observe the clinical efficacy of transcatheter hepatic arterial chemoembolization (TACE) in combination with B ultrasound guided percutaneous intrahepatic injection of 30% acetic acid (PAI) for primary massive hepatocellular carcinoma. Methods TACE was performed on 23 cases of massive hepatocellular carcinoma in the middle and late stages. PAI was performed 2 to 3 times after B-ultrasound guided 15 to 20 days after operation. Results After two cycles of treatment, the decrease of AFP and the reduction of tumor mass were compared before and after treatment. The difference was significant (P < 0.01). The 1- and 2-year survival rates were 91% and 82%, respectively. Conclusions TACE combined with ultrasound-assisted PAI for the treatment of middle and late massive hepatocellular carcinoma has good clinical efficacy.