包涵体肌炎是一种自身免疫性炎症性疾病。临 床表现为慢性进行性远端和近端肌肉无力,皮肤无损害。皮质类固醇激素和免疫抑制剂治疗无效。发病年龄一般多在50—70岁之间。肌肉活检组织病理上有炎性淋巴细胞浸润,肌纤维的坏死、再生,萎缩及肌纤维中有嗜酸性丝状包涵体和边缘空泡样肌纤维,肌质网中有嗜硷性包涵体,病因不清。 Inclusion body myositis is an autoimmune inflammatory disease. Chronic progressive clinical manifestations of distal and proximal muscle weakness, no damage to the skin. Corticosteroids and immunosuppressive agents are ineffective. Age of onset are generally more than 50-70 years old. Muscle biopsy histopathological inflammatory lymphocyte infiltration, muscle fiber necrosis, regeneration, atrophy and muscle fibers in the eosinophilic filamentous inclusions and marginal vacuolar muscle fibers, sarcoplasmic reticulum inclusions in the body, the cause is not clear .