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在严重失代偿性心力衰竭时,肾素-血管紧张素-醛固酮系统可被激活,这些患者的体循环血管阻力增高可能是与血管紧张素增高有关。为此,临床上曾有在严重充血性心力衰竭中应用肾素-血管紧张素-醛固酮系统阻断剂的报道。本文报告应用口服转化酶抑制剂巯甲丙脯氨酸(Captopril)治疗严重充血性心力衰竭的长期效果。
In severe decompensated heart failure, the renin-angiotensin-aldosterone system can be activated. The increased systemic vascular resistance in these patients may be related to an increase in angiotensin. For this reason, there have been clinical reports of the use of renin-angiotensin-aldosterone system blockers in severe congestive heart failure. This article reports the long-term efficacy of the oral invertase inhibitor captopril in the treatment of severe congestive heart failure.