【摘 要】
:
It has been accepted that bone marrow transplantation (BMT)is the only curative therapeutic option for certain hematologic malignancies.The southeast Asia regio
【机 构】
:
Department of Medicine
论文部分内容阅读
It has been accepted that bone marrow transplantation (BMT)is the only curative therapeutic option for certain hematologic malignancies.The southeast Asia region is an endemic area of hepatitis B virus(HBV)infection;thus,BMT using a hepatitis B surface antigen(HBsAg)-positive donor is occasionally unavoidable.Organ transplantation using a HBsAg-positive donor can lead to post-transplantation de novo HBV infection and severe HBV-related hepatitis if no effective prophylactic measures are taken prior to and after transplantation.In this report,a four-level approach was designed for a patient with chronic myeloid leukemia,beginning with a booster HBV vaccination before performing BMT with a HBsAg-positive donor.Prior to BMT,the HBV viral load of the donor was reduced to an undetectable level by antiviral therapy.After BMT,hepatitis B immunoglobulin was administered intramuscularly for 1 wk together with a long-term antiviral drug,lamivudine.One year after discontinuation of lamivudine,the patient is still free of HBV infection.
其他文献
用样带法调查了草原群落植物功能群组成沿水热梯度的变化.结果表明,随着海拔高度的降低,降水量的减少,热量和干燥度的增加,群落植物生活型功能群组成中,多年生杂类草的相对多
以耐Al性明显差异的 2个小麦基因型为材料 ,采用溶液培养试验和动力学方法研究了根际 pH变化、NH+ 4和NO-3 的吸收以及NO-3 还原与其耐Al性的关系。结果表明 ,A1胁迫下鉴 86
N+、Zn2+、Ar+离子束注入狐米草种子,其萌发率均明显降低.相同剂量,同种离子束抑制作用随加速电压(能量)的升高而加强.低能离子束对已萌发种子愈伤组织诱导率无显著影响,但能
目的构建融合表达Fas死亡信号激发域(Fas activation domain,FasAD)的重组载体FasAD-pTYB2.方法应用半巢式逆转录-多聚酶链反应(RT-PCR)技术克隆Fas死亡信号激发域cDNA片段Fa
目前,干细胞应用于临床治疗缺血性心脏疾病已取得了一定的疗效.然而干细胞移植后的的动态变化难以被量化,同时干细胞在体内的过程及其作用机理尚不清楚.分子影像作为一门新兴
经济全球化使得大型企业对外需要塑造新的客户关系,对内需要对日益退化的企业组织架构进行创新。本文介绍和分析大型企业宝钢集团的"总监制"组织建构创新的过程和内容,以期为
Pancreatic tumors are primary in most of the cases. Pancreatic metastases associated with other primary malignancies, especially pancreatic metastasis of leiomy
AIM: To explore the molecular mechanisms of action of paclitaxel and NM-3 on human gastric cancer in severe combined immune deficiency (SCID) mice.METHODS: Huma
Hilar tumors have proven to be a challenge to treat and manage because of their poor sensitivity to conventional therapies and our inability to prevent or to de
AIM: To compare the antiviral efficacy of adefovir (ADV) in lamivudine (LMV)-resistant patients with LMV treatment in nucleoside-na(i)ve patients, using serum s