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目的研究胃肠道淋巴瘤的临床病理特点。方法选择2010年3月～2012年9月间在我院进行诊治的6例胃肠道淋巴瘤患者,对淋巴细胞及上皮细胞运用多种抗体进行标记,对免疫组织进行化学染色。结果对所选的胃肠道淋巴瘤进行组织学分类,根据部位的不同分类如下。3例MACT发生在胃部,其中有2例发生了大B细胞转化,转化为高度恶性的MACT-LA。1例大B细胞淋巴瘤发生在胃,1例发生在回肠,1例Bccr-kitt淋巴瘤在结肠。其中胃及回肠穿孔各1例。结论胃肠道淋巴瘤多见于B细胞淋巴瘤,最多见的为MACT淋巴瘤,明确组织学分类对临床的诊断和治疗有重要的作用。
Objective To study the clinicopathological features of gastrointestinal lymphoma. Methods Six patients with gastrointestinal lymphoma diagnosed and treated in our hospital between March 2010 and September 2012 were selected and lymphocytes and epithelial cells were labeled with various kinds of antibodies for chemical staining of the immune tissues. Results The selected gastrointestinal lymphoma histological classification, according to the different parts of the classification as follows. Three cases of MACT occurred in the stomach, of which two had a large B cell transformation into a highly malignant MACT-LA. One large B-cell lymphoma occurred in the stomach, one in the ileum, and one Bccr-kitt lymphoma in the colon. One stomach and ileum perforation in 1 case. Conclusion Gastrointestinal lymphoma is more common in B-cell lymphoma, the most common is MACT lymphoma, a clear histological classification of clinical diagnosis and treatment have an important role.