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以回避反应为指标，检测了１９只２４月龄老年Ｗｉｓｔａｒ大鼠的学习记忆能力。于老年大鼠双侧海马或第三脑室移植新生大鼠颈上神经节后２周，观察到学习记忆能力显著改善，海马内移植后以避暗反应检查，进洞潜伏期自１７．５±１５．５ｓ延至３７６．７±２７０．８ｓ（ｐ＜０．０１）。同期非移植或假移植术大鼠的学习记忆能力仍处于较低水平。第三脑室内移植后以跳台法检测，大鼠为回避电击在平台停留５ｍｉｎ所需电击时间为１１．７±６．３ｓ，与移植前对照值６４．７±３２．３ｓ比较ｐ＜０．０１。行为实验后对移植区进行了荧光组织化学及电镜检查，结果表明，应用脑内移植技术改善老年大鼠的记忆损害可能与补充单胺类递质有关。
To avoid the reaction as an indicator, the detection of 19 24-month-old Wistar rats learning and memory ability. The hippocampus or the third ventricle in the aged rats were transplanted into the superior cervical ganglion of neonatal rats for 2 weeks, the learning and memory abilities were significantly improved. The intracranial hippocampus was evacuated to avoid darkness after transplanting. The incubation period was 17.5 ± 15 .5 s to 376.7 ± 270.8 s (p <0.01). The learning and memory ability of non-transplant or sham-operated rats was still at a low level during the same period. After the third intracerebroventricular transplantation, the method of step-by-step test was used. The shock time required for rats to stay on the platform for 5 minutes to avoid electric shock was 11.7 ± 6.3s, which was p <0 compared with 64.7 ± 32.3s before transplantation. 01. Fluorescent histochemistry and electron microscopy were performed on the transplanted area after the behavioral experiment. The results showed that the application of intracerebral transplantation to improve the memory impairment in aged rats may be related to the monoamine neurotransmitters.