【摘 要】
：
将DNA直接注射动物是接种特异性抗原、诱生免疫反应的一新手段。应用这一技术已成功地在小鼠、鸡及家畜中分别诱生了抗流感病毒、牛疱疹病毒1型及狂犬病毒的保护性免疫应答
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将DNA直接注射动物是接种特异性抗原、诱生免疫反应的一新手段。应用这一技术已成功地在小鼠、鸡及家畜中分别诱生了抗流感病毒、牛疱疹病毒1型及狂犬病毒的保护性免疫应答。但是,迄今尚不知这一新技术能否抗御病毒持续性感染。为此,本文作者将淋巴细胞脉络丛脑膜炎病毒(LCMV)核蛋白(NP)全基因序列克隆于pRCCMV质粒,构
Direct injection of DNA into animals is a new way to inoculate specific antigens and induce immune responses. Application of this technique has been successful in mice, chickens and domestic animals were induced anti-influenza virus, bovine herpes virus type 1 and rabies virus protective immune response. However, it is unknown so far whether this new technology can withstand the persistent virus infection. To this end, the author of the lymphocytic choriomeningitis (LCMV) nuclear protein (NP) gene sequence was cloned in pRCCMV plasmid structure
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