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目的:了解我院药物不良反应(ADR)的发生特点,促进临床合理用药。方法:对我院2004～2006年收集到的240例ADR报告,分别从报告人、药物种类、抗感染药物类别、给药途径、涉及器官系统等方面进行统计分析。结果:240例ADR报告来源于医师的占58.75%,涉及10大类药物,抗感染药物和中药制剂的ADR报告例数居第1、2位。静脉滴注药物引发的ADR占61.67%。ADR表现以皮肤损害最多。结论:应合理使用抗感染药物和中药制剂,以减少和避免ADR的发生。
Objective: To understand the occurrence of adverse drug reactions (ADR) in our hospital and to promote the rational use of clinical medicine. Methods: A total of 240 ADR reports collected in our hospital from 2004 to 2006 were analyzed statistically from the aspects of the reporter, drug type, anti-infective drug category, route of administration, and organ system involved. Results: 240 ADR cases were from physicians, accounting for 58.75%. The number of ADR cases involving 10 categories of drugs, anti-infective drugs and traditional Chinese medicines ranked No. 1 and No. 2. ADR caused by intravenous infusion accounted for 61.67%. ADR shows the most damage to the skin. Conclusion: Anti-infectives and traditional Chinese medicine should be used rationally to reduce and avoid the occurrence of ADR.