神经元特异性烯醇化酶(NSE)是神经元内糖酵解途径中同功酶之一。此酶最初在脑组织的提取物中发现,也存在于APUD细胞系统和神经外胚层肿瘤中。用NSE作为神经源性肿瘤的诊断与鉴别诊断的研究,国内外仅有20余例记载。但在临床病理工作中,对某些恶性周围神经外胚层肿瘤与其它小圆形细胞恶性肿瘤 Neuron-specific enolase (NSE) is one of the isozymes in the glycolytic pathway in neurons. This enzyme was originally found in extracts of brain tissue and is also present in the APUD cell system and neuroectodermal tumors. The use of NSE as a diagnostic and differential diagnosis for neurogenic tumors has only been documented in more than 20 cases at home and abroad. However, in clinical pathology work, some malignant peripheral ectodermal tumors and other small round cell malignancies