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目的：验证西沙必利（ｃｉｓａｐｒｉｄｅ）对非溃疡性消化不良的疗效。方法：采用双盲随机将８６例非溃疡性消化不良病人分为２组。西沙必利组４６例（男性３３例，女性１３例；年龄３６±ｓ８ａ），用西沙必利５ｍｇ，ｐｏ，ｔｉｄ；安慰剂组４０例（男性２９例，女性１１例；年龄３４±１０ａ），用安慰剂１片，ｐｏ，ｔｉｄ，２组均４ｗｋ为一个疗程。治疗后１～４ｗｋ通过直接提问来评价２组病人症状改善情况。结果：西沙必利对非溃疡性消化不良的症状改善率和症状严重程度的改善皆较安慰剂组有明显的效果（Ｐ＜０．０１）。结论：西沙必利对治疗非溃疡性消化不良有效。
Objective: To verify the efficacy of cisapride on non-ulcer dyspepsia. Methods: A total of 86 non-ulcer dyspeptic patients were randomly divided into 2 groups using a double-blind randomized trial. Cisapride group of 46 patients (33 males and 13 females; age 36 ± s8a), with cisapride 5mg, po, tid; placebo group 40 patients (29 males and 11 females; age 34 ± 10a) , Placebo 1, po, tid, 2 groups were 4wk for a course of treatment. 1 ~ 4wk after treatment by direct questioning to evaluate the 2 groups of patients to improve the situation. Results: Cisapride had a significant effect on improvement of symptom improvement and symptom severity of non-ulcer dyspepsia compared with placebo group (P <0.01). Conclusion: Cisapride is effective in treating non-ulcer dyspepsia.