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丙硫咪唑(albendazole,ABZ)是一种广谱抗蠕虫病药,1979年由美国研制成功。在法国、西非等地试用于肠道蠕虫病治疗,结果对人体内蛔虫、钩虫、蛲虫、鞭虫、绦虫等均有明显的驱虫作用。1983年英国Morris和法国Saimot 首先报道用ABZ 治疗包虫病获得疗效。国内1981年开始批量生产,供人畜使用,近几年试用于包虫病的治疗,成为继甲苯咪唑(mebendazole,MBZ)后一种更有前途的包虫病化疗药物。
Albendazole (ABZ) is a broad-spectrum antihelmintic drug developed in the United States in 1979. In France, West Africa and other places for the trial of intestinal helminth disease treatment, the results of the human body ascaris, hookworm, pinworm, whipworm, tapeworm and so on have significant deworming effect. In 1983, Morris, England and France, Saimot first reported the treatment of echinococcosis with ABZ. China started mass production in 1981 for human and animal use, and has been tried for the treatment of hydatid disease in recent years, becoming a more promising hydatid disease after mebendazole (MBZ).