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目的了解保山市吸毒人群的丙型肝炎病毒(HCV)感染现状及相关影响因素,为制定吸毒人群防治HCV的对策提供科学依据。方法对国家级艾滋病病毒(HIV)哨点保山市强制隔离戒毒所,2011年新入所的吸毒人员的监测资料进行分析,采用描述性统计方法分析吸毒者的人口学、行为学特征,同时采用单因素和多因素非条件Logistic回归模型分析HCV感染的影响因素。结果在调查的902名吸毒人员中,注射吸毒者占42.6%(384/902),其中共用针具者占18.5%(71/384);最近1年发生商业性行为者占21.6%(195/902);该人群HCV阳性检出率为44.8%(404/902),相关影响因素为:男性[比值比(OR)=0.232;95%可信区间(CI):0.100～0.540]、年龄(以≥41岁为参照)≤20岁(OR=0.229;95%CI:0.075～0.701)、注射吸毒(OR=12.149;95%CI:8.776～16.818)。结论保山市吸毒人群高危行为发生情况不容乐观。该人群HCV感染率较高,性别、年龄、注射吸毒是HCV感染的影响因素。今后应进一步加强社区清洁针具交换,这将有利于减少HCV在该人群中传播的风险。
Objective To understand the current status of hepatitis C virus (HCV) infection among drug users in Baoshan and its related factors to provide a scientific basis for the development of countermeasures against HCV in drug users. Methods The surveillance data of drug addicts who were admitted to compulsory isolation detoxification center in Baoshan, a national sentinel site of HIV were analyzed. Demographic and behavioral characteristics of drug users were analyzed by descriptive statistics. Factors and multivariate non-conditional logistic regression model were used to analyze the influencing factors of HCV infection. Results Of the 902 drug addicts surveyed, 42.6% (384/902) were injecting drug users, of whom 18.5% (71/384) had shared needles and 21.6% (21%) had commercial sex workers in the recent year 902). The positive rate of HCV in this population was 44.8% (404/902), and the related factors were male ratio [OR] = 0.232; 95% confidence interval (CI): 0.100-0.540) ≥40 years old (OR = 0.229; 95% CI: 0.075-0.701), injecting drug abuse (OR = 12.149; 95% CI: 8.776-16.818). Conclusion The occurrence of high-risk behaviors of drug addicts in Baoshan City is not optimistic. HCV infection in this population is higher, sex, age, injecting drug use is the influencing factor of HCV infection. Future community need to further strengthen the exchange of clean needles, which will help reduce the risk of HCV transmission in this population.