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目的:探讨Orbscan-II角膜地形图仪与角膜测厚仪对角膜测厚的结果差异的统计学及临床意义。方法:选115例204眼(右104眼,左100眼)分别行Orb-scan-II及超声测厚法测量角膜厚度,经统计学检验后进行分析。结果:204眼Orbscan-II所得结果为527.20±37.83,超声测厚法所得结果为525.25±34.83,行配对t检验,t=2.407,P=0.017,认为两种测量方法结果的差异有统计学意义。进一步将角膜厚度分4组进行配对t检验,角膜厚度<500μm时,Orbscan-II测厚(478.36±14.47)与超声测厚(478.3±20.15)差异无统计学意义,角膜厚度≥500,<550μm时,Orbscan-II测厚(527.88±17.32)与超声测厚(525.32±12.92)差异有统计学意义(P=0.027),角膜厚度≥550,<600μm时,Orbscan-II测厚(571.24±14.89)与超声测厚(568.04±13.82)差异有统计学意义(P=0.022),角膜厚度≥600μm时,Orbscan-II测厚(615.33±8.50)与超声测厚(615.33±14.29)差异无统计学意义。结论:传统的超声测厚与Orbscan-II对角膜测厚结果有一定差异,并具统计学意义,但在临床意义上二者仍有较好的相符性。
OBJECTIVE: To investigate the statistical and clinical significance of corneal thickness measurement by Orbscan-II corneal topography instrument and corneal thickness gauge. Methods: The corneal thickness was measured by Orb-scan-II and echocardiography in 115 eyes of 204 eyes (104 eyes in the right, 104 eyes in the left, and 100 eyes in the left). The corneal thickness was measured and analyzed by statistical test. Results: The result of Orbscan-II was 527.20 ± 37.83 in 204 eyes. The result of ultrasonic thickness measurement was 525.25 ± 34.83. Paired t-test was used, t = 2.407, P = 0.017. The difference between the two methods was statistically significant . The corneal thickness was further analyzed by paired t-test. There was no significant difference between Orbscan-II thickness measurement (478.36 ± 14.47) and ultrasonic thickness measurement (478.3 ± 20.15) when the corneal thickness was less than 500μm, corneal thickness≥500, <550μm (P = 0.027). Orbscan-II thickness measurement (571.24 ± 14.89) and corneal thickness≥550 (<600μm) were observed when Orbscan-II thickness was 527.88 ± 17.32 and 525.32 ± 12.92, respectively ) And ultrasonic thickness (568.04 ± 13.82) were statistically significant (P = 0.022). There was no significant difference between Orbscan-II thickness measurement (615.33 ± 8.50) and thickness measurement (615.33 ± 14.29) when corneal thickness≥600μm significance. Conclusion: The results of conventional ultrasonic thickness measurement and Orbscan-II corneal thickness measurement are different and statistically significant, but there is still a good agreement between the two in clinical significance.