In order to respond to the new engineering construction of the Ministry of Education, and explore the innovative talent training model of collaborative education and multidisciplinary integration, this paper relies on the software engineering teaching team of the School of Software Engineering, Beijing University of Posts and Telecommunications, through the implementation of the collaborative education project of the Ministry of Education, and proposes the multi-course collaborative practice teaching system, through the reasonable cross-fusion of the practical links of the 5 software engineering courses in the college, realizes the multi-course collaborative education and reasonable cross-fusion of courses, shares practical project resources, introduces new enterprise technologies, and guides students' innovation and entrepreneurship provide a meaningful reference for the collaborative arrangement of teaching content and cross-disciplinary integration in the current university education system.