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目的了解手足口病出现脱甲症发生率、脱甲症的危害以及控制措施。方法对实验室确诊由柯萨奇病毒A16(Cox A16)病毒感染的手足口病病例4例,肠道病毒71型(EV 71)病毒感染的手足口病病例4例,柯萨奇病毒A6(Cox A6)感染的手足口病病例25例进行临床跟踪观察。医务人员经统一培训后使用统一调查表,每天上午9:00仔细检查并记录结果,毎个病例连续观察3月。结果本次追踪观察到Cox A6感染的手足口病病例出现脱甲症,而Cox A16与EV 71病毒感染的手足口病未观察到脱甲现象。Cox A6感染的手足口病病例出现脱甲症的几率为52.00%,出现脱甲症后平均经过15.6 d痊愈。结论手足口病病例后期可出现脱甲症,不留后遗症,危害程度不大。
Objective To understand the incidence of hand-foot-mouth disease dementia, demethylation hazards and control measures. Methods Four cases of hand-foot-mouth disease (CIM-A16) were confirmed in the laboratory. Four cases of hand-foot-mouth disease (EV-71), four Coxsackievirus A6 Cox A6) infection in hand, foot and mouth disease in 25 cases of clinical follow-up observation. After uniform training, medical staffs use a unified questionnaire to carefully examine and record the results at 9:00 am every day, and continuously observe March in each case. Results The follow-up observation showed that there were cases of hand-foot-mouth disease in Cox A6-infected patients, and no detoxification was observed in hand-foot-mouth disease in Cox A16 and EV71 viruses. Cox A6 infection in hand, foot and mouth disease cases of the incidence of demetonation was 52.00%, after the onset of demethylation after an average of 15.6 d healed. Conclusions Hand-foot-mouth disease can occur in the later stage of demethylation, leaving no sequelae and little harm.