目的　探讨二种不同肺活检方法的临床价值 ,以提高诊断准确率。方法　回顾我院 1988～ 2 0 0 0年经影像学、痰细胞学、细菌学及纤维支气管镜 (以下简称纤支镜 )检查不能确诊的患者 2 93例 ,对两种不同方法的肺活检结果进行比较分析。结果　经皮肺穿刺活检 148例 ,分别采用X线、CT、B超引导方法 ,其活检阳性率为 87.8% ;经纤支镜肺穿刺活检 145例 ,活检阳性率为 79.3%。并发症发生率分别为 2 3.6 %和 2 1.4 %。结论　采用肺活检的方法不同 ,其结果和临床意义不同 ,经皮肺活检以CT引导下的方式 ,诊断准确率最高 Objective To investigate the clinical value of two different lung biopsy methods in order to improve the diagnostic accuracy. Methods A retrospective review of our hospital from 1988 to 2000 by imaging, sputum cytology, bacteriology and bronchoscopy (hereinafter referred to as bronchoscopy) can not be diagnosed in patients with 2 93 cases of lung biopsy results of two different methods For comparative analysis. Results 148 cases of percutaneous pulmonary biopsy, respectively, using X-ray, CT, B-guided method, the biopsy positive rate was 87.8%; bronchoscopy lung biopsy in 145 cases, the biopsy positive rate was 79.3%. The complication rates were 23.6% and 21.4%, respectively. Conclusion Different methods of using lung biopsy, the results and clinical significance, percutaneous lung biopsy under the guidance of CT, the highest diagnostic accuracy