甲磺酸多沙唑嗪是一种用于治疗高血压和良性前列腺增生的选择性的α肾上腺素能受体阻滞剂。简便、高效的液相色谱法已证实可以用于多沙唑嗪血浆药物浓度的定量分析。Kwon YH等人进行了一项研究,结合应用反相C18色谱柱和由水:甲基氰:三乙胺(68:32:0.2 v/v,pH 5.0)按比例构成的流速为1.2mL/min的移动相对多沙唑嗪和派唑嗪(内参照)进行了分离。荧光检测参数分别设置为246nm(激发光波长)和389 nm(发射光 Doxazosin mesylate is a selective alpha adrenergic receptor blocker used to treat hypertension and benign prostatic hyperplasia. Simple and efficient liquid chromatography has proved to be useful for the quantitative analysis of doxazosin plasma drug concentrations. A study by Kwon YH et al., In combination with a reversed-phase C18 column and a flow rate of 1.2 mL / mL with a scaled-up ratio of water: methylcyanide: triethylamine (68:32: 0.2 v / v, pH 5.0) min relative to doxazosin and pyrazosin (internal reference). The fluorescence detection parameters were set to 246 nm (excitation light wavelength) and 389 nm (emission light, respectively)